Search results for: 'Smad'

Cat. No.	Name	CAS No.	Description
KI0043	Y-27632 DIHYDROCHLORIDE	146986-50-7	Y-27632 is a potent, highly specific, cell-permeable inhibitor of Rho kinase (ROCK) with K_{i of 140 nM....}
KI2375	Wnt-C59 (C59)	1243243-89-1	Wnt-C59 is a potent and selective Wnt signaling antagonist with an IC50 less than 0.11 nM....
KI1235	Thiazovivin	1226056-71-8	Thiazovivin is a novel ROCK inhibitor with an IC50 value of about 0.6 µM....
KI2431	SC144	895158-95-9	SC144 is a first-in-class orally active small-molecule glycoprotein 130 (gp130) inhibitor....
KI4216	SB505124	694433-59-5	....
KI0072	Saracatinib	379231-04-6	Saracatinib is a novel Src family kinase/Abl dual-kinase inhibitor for c-Src and v-Abl with IC50 values of 2.7 and 30 nM, respectively....
KI0032	Ponatinib	943319-70-8	Ponatinib is a novel multi-targeted tyrosine kinase inhibitor (TK) that potently inhibits native and mutant BCR-ABL....
KI2514	NU9056	1450644-28-6	NU9056 is a Tip60 specific inhibitor....
KI2337	NSC66811	6964-62-1	NSC66811 is a murine double minute 2 (MDM2) antagonist....
KI2341	NSC319726	71555-25-4	NSC319726 is a p53R175 mutant reactivator....
KI0289	Nilotinib	641571-10-0	Nilotinib inhibits the kinases BCR-ABL, KIT, LCK, EPHA3, EPHA8, DDR1, DDR2, PDGFRB, MAPK11 and ZAK....
KI4125	LY364947	396129-53-6	....
KI0505	LY2109761	700874-71-1	LY2109761 is a selective chemical competitive inhibitor of the transforming growth factor β Type II receptor (TβR) kinases....
KI2080	LX 1606	1033805-22-9	LX-1606 is a tryptophan hydroxylase (TPH) inhibitor with antiserotonergic activity....
KI1121	LDN 193189	1062368-24-4	LDN 193189 is a potent SMAD 1/5/8 phosphorylation inhibitor....
KI2381	KY02111	1118807-13-8	KY02111 is a Wnt signaling inhibitor....
KI0301	Imatinib	152459-95-5	Imatinib is a 2-phenylaminopyrimidine derivative that functions as a multi-target inhibitor of tyrosine kinase enzymes with IC50 values of 0.6, 0.1 and 0.1 μM for v-Abl, c-kit and PDGFR, respectively....
KI2216	GW788388	452342-67-5	GW788388 is a potent and selective TGF-β type I receptor inhibitor....
KI4700	Go 6983	133053-19-7	....
KI2345	GDC-0152	873652-48-3	GDC-0152 is a potent antagonist of cellular IAP1/2 (cIAP1/2), melanoma IAP (ML-IAP), and X chromosome-linked IAP (XIAP)....