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KA4126 Caspase 8 (Ab-347) Antibody Quote Quote

Overview

Product NameCaspase 8 (Ab-347) Antibody
ApplicationsWB, IHC
ConcentrationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
ImmunogenThe antiserum was produced against synthesized non-phosphopeptide derived from human Caspase 8 around the phosphorylation site of serine 347 (C-P-S-L-A).
Specificity/SensitivityCaspase 8 (Ab-347) antibody detects endogenous levels of total Caspase 8 protein.

Product Information

SourceRabbit
Research AreasCancer/Apoptosis
Alternative NamesApoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 precursor, EC 3.4.22.-, FADD-homologous ICE/CED-3- like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, ICE8, MACH, MCH5, MORT1-associated CED-3 homolog
Storage/StabilityStore at -20/1 year
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Species ReactivityHuman, Mouse, Rat
Application NotesWB: 1:500~1:3000 IHC: 1:50~1:100 ELISA: 1:1000
IHC
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Caspase 8 (Ab-347) antibody (#B0059). The picture on the right is treated with the synthesized peptide.
ReferencesDaniel R. Beisner, J. Immunol., Sep 2005; 175: 3469 - 3473. Peter J. Wild, Mol. Cancer Ther., Apr 2005; 4: 516 - 528. A.V. TIMOFEEVA, Ann. N.Y. Acad. Sci., Dec 2006; 1091: 319 - 335. Leon Tourian, J. Cell Sci., Dec 2004; 117: 6459 - 6471.
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