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KKS0062Cathepsin B Inhibitor Screening Kit (Fluorometric)100 assays$864.5

Overview

Product NameCathepsin B Inhibitor Screening Kit (Fluorometric)
Kit SummaryDetection method - Fluorescence
Applications - Screen/study/characterize potential inhibitors of Cathepsin B
Features BenefitSimple & convenient
High-throughput adaptable assay to screen/study/characterize the potential inhibitors of Cathepsin B
Cathepsin B inhibitor, F-F-FMK is included in the kit
Kit ComponentsCTSB Reaction Buffer
CTSB Reagent
Cathepsin B (human)
CTSB Substrate, Ac-RR-AFC (10 mM)
CTSB Inhibitor (F-F-FMK, 1 mM)
Storage Conditions-20
Shipping ConditionsGel back
DescriptionCathepsin B (CTSB, EC 3.4.22.1) is a lysosomal cysteine proteinase that is suggested to participate in intracellular degradation and turnover of proteins. It has also been implicated in tumor invasion and metastasis. Cathepsin B Inhibitor Screening Kit utilizes the ability of Cathepsin B to cleave the synthetic AFC based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin B-specific inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This simple and high-throughput adaptable assay kit can be used to screen/study/characterize the potential inhibitors of Cathepsin B.

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Our products are used for research, laboratory and further evaluation purposes. They are not for human use.