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KKS0051Cathepsin G?Assay Kit *Fluorimetric*100 assays$664.3

Overview

Product NameCathepsin G?Assay Kit *Fluorimetric*
Kit SummaryDetection method- Absorbance (405 nm)
Sample type- Cell and tissue lysates, serum
Applications- Detects alternative proteolytic enzymes such as the lysosomal cathepsin G proteases that can initiate or propagate proapoptotic signals
Features BenefitFast, robust and convenient
Cathepsin-G assay is straightforward, and can be adapted to 96-well plate assays
Kit ComponentsAssay Buffer
Substrate
Cathepsin G Inhibitor
pNA Standard (0.1 M)
Positive Control
Storage Conditions-20
Shipping ConditionsGel back
DescriptionCathepsin G is an enzymatic protein belonging to the peptidase or protease families. The protein is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In Cathepasin G Activity assay Kit, Cathepsin G will cleave the substrate and release the dye group, pNA (4-Nitroaniline), which can be detected at 405 nm. In presence of the Cathepsin G specific inhibitor, the cleavage will be stopped. The kit provides a rapid, simple, sensitive, and reliable test suitable for the activity of Cathepsin G.

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