Cat. No. Name Size Price Add Cart
KKS0069Cathepsin S Inhibitor Screening Kit100 assays$864.5

Overview

Product NameCathepsin S Inhibitor Screening Kit
Kit SummaryDetection method - Fluorescence
Applications - Screen/study/characterize potential inhibitors of Cathepsin S
Features BenefitSimple & convenient
High-throughput adaptable assay to screen/study/characterize the potential inhibitors of Cathepsin S
Cathepsin S inhibitor, Z-FF-FMK is included in the kit
Kit ComponentsCTSS Reaction Buffer
Cathepsin S (human)
CTSS Substrate, Z-VVR-AFC (10 mM)
CTSS Inhibitor (Z-FF-FMK, 1 mM)
Storage Conditions-20
Shipping ConditionsGel back
DescriptionCathepsin S (CTSS, EC 3.4.22.27) is a lysosomal cysteine proteinase that is suggested to participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. Cathepsin S Inhibitor Screening Kit utilizes the ability of Cathepsin S to cleave the synthetic AFC based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin S inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This high-throughput adaptable assay kit is simple, sensitive, and rapid tool to screen the potential inhibitors of Cathepsin S.

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