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Cat. No. Name Size Price Add Cart
KKS0043HDAC3 Inhibitor Screening Kit (Fluorometric)100 assays$846.3

Overview

Product NameHDAC3 Inhibitor Screening Kit (Fluorometric)
Kit SummaryDetection method- Fluorescence (Em/Ex = 380/500 nm)
Sample type- Testing candidate HDAC3 inhibitors
Applications- Suitable for high throughput screening of HDAC3 inhibitors
Features BenefitFast and convenient
Kit contains the necessary reagents for testing putative HDAC3 inhibitors
Kit ComponentsHDAC3 Assay Buffer
HDAC3 Substrate
HDAC3 Enzyme
Developer
Trichostatin A
Storage Conditions-20
Shipping ConditionsGel back
DescriptionHistone deacetylases (HDACs) represent a large family of enzymes identified as key regulators of nucleosomal histone acetylation, a major event that controls eukaryotic gene transcription and are classified into three groups. They are believed to be involved in important biological activities, such as cell differentiation, proliferation, apoptosis, and senescence. In HDAC3 Inhibitor screening Kit, HDAC3 and developer will deacetylate and cleave the substrate [Arg-His-Lys-Lys(Ac)-AFC] to release the quenched fluorescent group (AFC), which can be detected at Em/Ex=380/500 nm. In presence of a HDAC3 inhibitor, the cleavage will be inhibited. The kit provides a rapid, simple, sensitive, and reliable test, which is also suitable for high throughput screening of HDAC3 inhibitors. Trichostatin A (TSA) is included as a control inhibitor to compare the efficacy of the test inhibitors.

Please click here to fill online order form, and we will make sure to supply you product with detail information. This process usually takes between 24 to 48 hours, depending on products stock avaliability. All inquires and subsequent projects are handled in the strictest confidence and will be backed by a confidentiality agreement if required.
KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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