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Cat. No. Name Size Price Add Cart
KA4030 HER2 (Phospho-Tyr1248) Antibody Quote Quote

Overview

Product NameHER2 (Phospho-Tyr1248) Antibody
ApplicationsWB, IHC
ConcentrationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
ImmunogenHER2 (phospho-Tyr1248) antibody detects endogenous levels of HER2 only when phosphorylated at tyrosine 1248.
Specificity/SensitivityHER2 (phospho-Tyr1248) antibody detects endogenous levels of HER2 only when phosphorylated at tyrosine1248.

Product Information

SourceRabbit
Research AreasPhospho-specific
Alternative NamesC-erbB-2; EC 2.7.10.1; Epidermal growth factor receptor-related protein; ErbB2; HER2; kinase ErbB2; MLN 19; NEU; NEU proto-oncogene; NGL; p185erbB2; Receptor protein-tyrosine kinase erbB-2; Receptor protein-tyrosine kinase erbB-2 precursor; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
Storage/StabilityStore at -20/1 year
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Species ReactivityHuman, Mouse, Rat
Application NotesWB: 1:500~1:3000 IHC: 1:50~1:100 ELISA: 1:20000
WB
Western blot analysis of extracts from HepG2 cells, using HER2 (phospho-Tyr1248) antibody. The lane on the right is treated with the synthesized peptide.

Western blot analysis of extracts from HepG2 cells (Lane 2), using HER2 (Phospho-Tyr1248) Antibody. The lane on the left is treated with synthesized peptide.
IHC
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HER2 (phospho-Tyr1248) antibody. The picture on the right is treated with the synthesized peptide.
ReferencesRamsauer VP, et al. (2003) J Biol Chem; 278(32): 30142-7. Jepson S, et al. (2002) Oncogene; 21(49): 7524-32. Ren Z, et al. (2002) J Biol Chem; 277(41): 38486-93. Eppenberger-Castori S, et al. (2001) J Clin Oncol; 19(3): 645-56.
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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