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KKS0097MMP-3 Inhibitor Screening Kit (Fluorometric)100 assays$846.3

Overview

Product NameMMP-3 Inhibitor Screening Kit (Fluorometric)
Kit SummaryDetection method- Fluorescence
Sample type- Test inhibitors for MMP-3
Applications- The kit can be used to screen inhibitors of MMP-3
Features BenefitFast and convenient
The assay is simple, reliable and ensures accuracy and consistency when working with multiple samples
Kit ComponentsMMP-3 Assay Buffer
MMP-3 Substrate
MMP-3 Enzyme (lyophilized)
Inhibitor Control (0.1 mM GM6001)
Storage Conditions-20
Shipping ConditionsGel back
DescriptionThe matrix metalloproteinase-3 (MMP-3, stromelysin-1) exhibits a number of activities that would make it a particularly good tumor promoter. Like several other MMPs, MMP-3 was first cloned and later recloned as a cancer-specific gene. In addition to degrading numerous extracellular matrix components, MMP-3 can activate gelatinase B, the collagenases and several serpin-type serine proteinase inhibitors. Moreover, it can release a number of cell surface molecules, including E-cadherin, a known contributor to cancer development. In MMP-3 Inhibitor Screening Assay Kit, MMP-3 hydrolyzes a specific FRET substrate to release the quenched fluorescent group Mca, which can be detected fluorometrically. The kit provides a rapid, simple, sensitive, and reliable test suitable as a high throughput screening assay of MMP-3 inhibition.

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Our products are used for research, laboratory and further evaluation purposes. They are not for human use.