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KA3863 SHP-2 (Phospho-Tyr580) Antibody Quote Quote

Overview

Product NameSHP-2 (Phospho-Tyr580) Antibody
ApplicationsWB, IHC
ConcentrationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human SHP-2 around the phosphorylation site of tyrosine 580 (R-V-YP-E-N).
Specificity/SensitivitySHP-2(phospho-Tyr580) antibody detects endogenous levels of SHP-2 only when phosphorylated at tyrosine 580.

Product Information

SourceRabbit
Research AreasPhospho-specific
Alternative NamesEC 3.1.3.48, PTN11, PTP-1D, PTP-2C, PTP2C, PTPN11, Protein-tyrosine phosphatase 2C, Protein-tyrosine phosphatase, non-receptor type 11, SH-PTP2, SH-PTP3, SHPTP2
Storage/StabilityStore at -20/1 year
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Species ReactivityHuman: Tyr580; Mouse: Tyr584; Rat: Tyr580
Application NotesWB: 1:500~1:3000 IHC: 1:50~1:100 ELISA: 1:40000
IHC
Immunohistochemical analysis of paraffin-embedded human brain tissue, using SHP-2 (phospho-Tyr580) antibody. The picture on the right is treated with the synthesized peptide.
ReferencesMinako Yamaoka-Tojo, Arterioscler. Thromb. Vasc. Biol., Sep 2006; 26: 1991 - 1997. Liang Liang, Endocrinology, Sep 2000; 141: 3328. Tony Avril, J. Immunol., Dec 2004; 173: 6841 - 6849. Laura A. Maile, Mol. Biol. Cell, Sep 2003; 14: 3519.
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