EGFR

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    Cat. No. Name CAS No. Description
    KI1299 AEE788 497839-62-0 AEE788 is a novel multitargeted inhibitor of EGFR, ErbB2, KDR, and Flt-1 with IC50 values of 2, 6, 77 and 59 nM, respectively....
    KI6066 AG 18 118409-57-7 ....
    KI0514 AG-1478 153436-53-4 AG-1478 is an inhibitor of the EGFR tyrosine kinase....
    KI6074 AG-1517 153436-54-5 ....
    KI3645 Apatinib 811803-05-1 Apatinib, also known as YN968D1, is a tyrosine kinase inhibitor that selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2, also known as KDR) with IC50 of 1nM [1]....
    KI4027 Apixaban 503612-47-3 ....
    KI0443 Axitinib 319460-85-0 Axitinib is a potent and selective inhibitor of VEGF receptor tyrosine kinase (RTK) 1, 2, and 3....
    KI3884 AZD2858 486424-20-8 ....
    KI1303 AZD8931 848942-61-0 AZD8931 is a reversible, ATP competitive inhibitor of epidermal growth factor receptor (EGFR; erbB1), erbB2 (human epidermal growth factor receptor 2), and erbB3 receptor with IC50 of 4, 3 and 4 nM, respectively....
    KI0068 BIBW2992 439081-18-2 BIBW2992 is an irreversible inhibitor of ErbB family with IC50s of 0.5, 14 and 1 nM for epidermal growth factor receptor (EGFR) (ErbB1/HER1), HER2 and HER4 kinases....
    KI4188 BPI-2009H 610798-31-7 ....
    KI4010 C646 328968-36-1 ....
    KI0433 CI-1033 (Canertinib) 267243-28-7 CI-1033 is an irreversible Pan-erbB tyrosine kinase inhibitor....
    KI3290 CO-1686 1374640-70-6 CO-1686 is a potent and mutant-selective EGFR inhibitor....
    KI1220 CUDC-101 1012054-59-9 CUDC-101 is a potent HDAC, EGFR and HER2 inhibitor with IC50 values of 4.4, 2.4, and 15.7 nM, respectively....
    KI0437 Dovitinib Dilactic acid (TKI258 Dilactic acid) 852433-84-2 Dovitinib is a highly potent inhibitor of vascular endothelial growth factor receptor (VEGFR) 1, VEGFR2, VEGFR3, platelet-derived growth factor receptor (PDGFR) β, and fibroblast growth factor growth (FGFR)1, FGFR2, and FGFR3 (fibroblast growth factor receptors 1, 2, and 3)....
    KI2658 E-7050 928037-13-2 E-7050 is novel small molecule inhibitor of the c-Met and VEGFR-2 tyrosine kinases....
    KI3882 EPZ004777 1338466-77-5 ....
    KI0303 Erlotinib Hydrochloride 183319-69-9 Erlotinib is a selective, orally available small-molecule inhibitor of the HER1/EGFR tyrosine kinase domain, used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer....
    KI0309 Gefitinib 184475-35-2 Gefitinib, a synthetic anilinoquinazoline, directly and specificly inhibits tyrosine kinase (TK) phosphorylation on the epidermal growth factor receptor (EGFR) by competing for the ATP-binding site, which leads to suppression of the EGFR pathway (HER-kinase axis)....

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