HER2

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    Cat. No. Name CAS No. Description
    KI1299 AEE788 497839-62-0 AEE788 is a novel multitargeted inhibitor of EGFR, ErbB2, KDR, and Flt-1 with IC50 values of 2, 6, 77 and 59 nM, respectively....
    KI0465 AG879 148741-30-4 AG 879 is widely used specific Tyr kinase inhibitor for ErbB2 and FLK-1 (a VEGF receptor)....
    KI2826 ARRY-380 937265-83-3 ARRY-380 is a potent and selective HER2 (also known as ErbB2) inhibitor....
    KI3415 AV-412 451493-31-5 AV-412 is a potent dual inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 tyrosine kinases, including the mutant EGFRL858R,T790M....
    KI1303 AZD8931 848942-61-0 AZD8931 is a reversible, ATP competitive inhibitor of epidermal growth factor receptor (EGFR; erbB1), erbB2 (human epidermal growth factor receptor 2), and erbB3 receptor with IC50 of 4, 3 and 4 nM, respectively....
    KI0068 BIBW2992 439081-18-2 BIBW2992 is an irreversible inhibitor of ErbB family with IC50s of 0.5, 14 and 1 nM for epidermal growth factor receptor (EGFR) (ErbB1/HER1), HER2 and HER4 kinases....
    KI0433 CI-1033 (Canertinib) 267243-28-7 CI-1033 is an irreversible Pan-erbB tyrosine kinase inhibitor....
    KI3460 CP-724714 537705-08-1 CP-724,714 is a selective inhibitor of epidermal growth factor 2(erbB/2) tyrosine kinase....
    KI1220 CUDC-101 1012054-59-9 CUDC-101 is a potent HDAC, EGFR and HER2 inhibitor with IC50 values of 4.4, 2.4, and 15.7 nM, respectively....
    KI0431 Lapatinib 231277-92-2 Lapatinib is a selective inhibitor of both epidermal growth factor receptor (EGFR) and HER-2 tyrosine kinases with IC50 of 10.2 and 9.8 nM, respectively....
    KI4363 Nelarabine 121032-29-9 ....
    KI0084 Neratinib 698387-09-6 Neratinib is a dual inhibitor of the human epidermal growth factor receptor 2 (HER2) and epidermal growth factor receptor (EGFR) kinases....
    KI1063 PF299804 1110813-31-4 PF299804 is an irreversible Pan-ERBB inhibitor....
    KI3937 SCH727965 779353-01-4 ....
    KI1499 Varlitinib 845272-21-1 Varlitinib is a reversible, ATP-competitive inhibitor with nanomolar potency in both in vitro and in cell-based assays showing strong activity against EGFR, ErbB2 and ErbB4....

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