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Cat. No. Name Size Price Add Cart
KP0127 2837b, Hemoglobin Fragment, Plasmepsin II (PM II) substrate, EDANS/ DABCYL 1 mg $232

Product Information

Product Name2837b, Hemoglobin Fragment, Plasmepsin II (PM II) substrate, EDANS/ DABCYL
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1896
Storage-20°C
Sequence
(One-Letter Code)		EDANS-CO-CH2-CH2-CO-ALERMFLSFP-Dap(DABCYL)OH
Sequence
(Three-Letter Code)		EDANS - CO - CH2 - CH2 - CO - Ala - Leu - Glu - Arg - Met - Phe - Leu - Ser - Phe - Pro - Dap(DABCYL) - OH
DescriptionThe sequence of this synthetic peptide is based on the primary site of cleavage by plasmepsin II (PM II) within hemoglobin (Hb), and numbering of the peptide corresponds to the residue within the α-chain of Hb. Plasmepsins are involved in the early steps of hemoglobin degradation. They are able to recognize intact hemoglobin and make an initial cleavage in the B helix of the hemoglobin α-chain between Phe-33 and Leu-34.
ReferencesIstvan, E. and D. Goldberg. J. Biol. Chem. 280, 6890 (2005); Liu, J. et al. J. Biol. Chem. 281, 38682 (2006).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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