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Cat. No. Name Size Price Add Cart
KP0141 37, 40 GAP26, Connexin Mimetic 1 mg $80

Product Information

Product Name37, 40 GAP26, Connexin Mimetic
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1548.8
Storage-20°C
Sequence
(One-Letter Code)		VCYDQAFPISHIR
Sequence
(Three-Letter Code)		H - Val - Cys - Tyr - Asp - Gln - Ala - Phe - Pro - Ile - Ser - His - Ile - Arg - OH
DescriptionThis peptide corresponds to the GAP26 domain of the extracellular loop of the major vascular connexins (Cx37, Cx40), designated as 37,40Gap 26 according to Cx homology. It was used to investigate the role of gap junctions in the spread of endothelial hyperpolarizations evoked by cyclopiazonic acid (CPA) through the wall of the rodent iliac artery. The gap junction plaques constructed from Cx37 and Cx40 were abundant in the endothelium. This peptide provides inhibitory effects against subintimal hyperpolarization.
ReferencesChaytor, A. et al. British J. Pharmacol. 144, 108 (2005), Griffith, T. et al. PNAS 102, (7008).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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