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KP0159 5 - FAM - GRPRTSSFAEG 1 mg $237

Product Information

Product Name5 - FAM - GRPRTSSFAEG
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1522.6
Storage-20°C
Sequence
(One-Letter Code)
5-FAM-GRPRTSSFAEG
Sequence
(Three-Letter Code)
5 - FAM - Gly - Arg - Pro - Arg - Thr - Ser - Ser - Phe - Ala - Glu - Gly - OH
DescriptionCrosstide is a peptide analog of glycogen synthase kinase-3 (GSK-3) that functions as a natural substrate for Akt/PKB. It displays similar specificities towards PKBα, PKBβ and PKBγ isoforms. It is also recognized by MAPKAP kinase-1 and p70S6K. The fluorescent and biotinlyated peptides demonstrate similar enzyme activities.
ReferencesRef: Dai, F. et al. Biochem. Biophys. Res. Commun. 293, 1191 (2002). Meier, R. et al. J. Biol. Chem. 272, 30491 (1997); Chan, TO. et al. Ann. Rev. Biochem. 68, 965 (1999).
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