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Cat. No. Name Size Price Add Cart
KP0260 Annexin 1 (ANXA - 1, Ac 2 - 26) 1 mg $174

Product Information

Product NameAnnexin 1 (ANXA - 1, Ac 2 - 26)
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 3041.4
Storage-20°C
Sequence
(One-Letter Code)		Ac-AMVSEFLKQAWIENEEQEYVVQTVK
Sequence
(Three-Letter Code)		Ac - Ala - Met - Val - Ser - Glu - Phe - Leu - Lys - Gln - Ala - Trp - Ile - Glu - Asn - Glu - Glu - Gln - Glu - Tyr - Val - Val - Gln - Thr - Val - Lys - OH
DescriptionThis acetylated peptide is amino acids 2 to 28 N-terminus fragment of Annexin 1 (ANXA1). ANXA1, previously referred to as lipocortin 1 or LC1, is a member of the annexin superfamily that has potent leukocyte antimigratory activity. This fragment, as well as the full-length ANXA1, may significantly reduce polymorphonuclear leukocyte (PMN) influx in mice. ANXA1 and ANXA1 mimetics, such as Ac (2-12), inhibit recruitment of neutrophils in acute and chronic inflammation. This peptide is able to inhibit neutrophil extravasation.
ReferencesPerretti, M. et al. Nat Med 8, 1296 (2002); Mylinh, LA. et al. FASEB J 15, 2247 (2001); Perretti, M. et al. Am J Pathol 158, 1969 (2001); Lim, L. et al. Proc Natl Acad Sci USA 95, 14535 (1998).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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