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KP0277 Apolipoprotein E4 (94 - 108) 1 mg $80

Product Information

Product NameApolipoprotein E4 (94 - 108)
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1730.9
Storage-20°C
Sequence
(One-Letter Code)
SELEEQLTPVAEETR
Sequence
(Three-Letter Code)
H - Ser - Glu - Leu - Glu - Glu - Gln - Leu - Thr - Pro - Val - Ala - Glu - Glu - Thr - Arg - OH
DescriptionThis peptide is derived from apolipoprotein E4. Apolipoprotein is a plasma protein present in various organs, such as the spleen, kidney, liver, and brain that binds low-density lipoprotein receptors and participates in cholesterol transport and redistribution. Apoliprotein E also functions in peripheral nerve injury and regeneration, immunoregulation, and regulation of cell growth and differentiation. Apolipoprotein E4 has been implicated in sporadic and late onset Alzheimer's disease.
ReferencesCandiano, G. et al, Electrophoresis 22, 1819 (2001); Poirier, J. et al. Proc Natl Acad Sci 92, 12260 (1995); Mahley, RW. Science 240, 622 (1988).
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