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KP0282 Aquaporin - 2 (254 - 267), pSER261, human 1 mg $122

Product Information

Product NameAquaporin - 2 (254 - 267), pSER261, human
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1713.8
Storage-20°C
Sequence
(One-Letter Code)
RQSVELH-pS-PQSLPR
Sequence
(Three-Letter Code)
H - Arg - Gln - Ser - Val - Glu - Leu - His - pSer - Pro - Gln - Ser - Leu - Pro - Arg - OH
DescriptionThis peptide is a fragment of the human aquaporin-2 (AQP2) phosphorylated at Ser261. Protein phosphorylation plays a key role in vasopressin signaling in renal-collecting duct. Phosphorylation at several AQP2 residues including Ser256 and Ser261, is altered in response to vasopressin. It is possible that both sites are involved in vasopressin-dependent AQP2 trafficking.
ReferencesNielsen, S. et al. PNAS 90, 11663 (1993); Hoffert, J. et al. PNAS 103, 7159 (2006).
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