| Cat. No. |
Name |
CAS No. |
Description |
|
KI3355 |
INO-1001 |
3544-24-9 |
INO-1001 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor....
|
|
KI0207 |
INCB018424 |
941678-49-5 |
INCB018424 is a potent and selective inhibitor of JAK1 (Janus kinase) and JAK2 with IC50 of 3.3 and 2.8 nM, respectively....
|
|
KI0002 |
Hesperadin |
422513-13-1 |
Hesperadin is an indolinone inhibitor of human Aurora B with an IC50 of 250 nM....
|
|
KI4250 |
GSK343 |
1346704-33-3 |
....
|
|
KI1161 |
GSK1070916 |
942918-07-2 |
GSK1070916 is a novel, potent and selective ATP competitive inhibitor of Aurora B and Aurora C kinases with IC50 values of 3.5 and 6.5 nM, respectively....
|
|
KI4757 |
GSK J4 |
1373423-53-0 |
....
|
|
KI1228 |
Givinostat |
732302-99-7 |
Givinostat is a potent inhibitor of HDAC with IC50 values of 10, 7.5 and 16 nM for HD2, HD1-B and HD1-A, respectively....
|
|
KI3440 |
EX 527 |
49843-98-3 |
EX-527 is a potent and specific small-molecule inhibitor of SIRT1....
|
|
KI2263 |
EPZ005687 |
1396772-26-1 |
EPZ005687 is a potent and selective small-molecule inhibitor of enhancer of zeste homolog 2 (EZH2)....
|
|
KI0035 |
Entinostat |
209783-80-2 |
Entinostat is an oral class I isoform-selective histone deacetylases (HDAC) inhibitor with IC50s of 0.51 and 1.7 µM for HDAC1 and HDAC3, respectively....
|
|
KI0990 |
ENMD-2076 L-(+)-Tartaric acid |
1291074-87-7 |
ENMD-2076 is a potent inhibitor of Aurora A and Aurora B with IC50s of 14 and 350 nM, respectively....
|
|
KI6039 |
Dimethyloxaloylglycine |
89464-63-1 |
....
|
|
KI0927 |
Decitabine |
2353-33-5 |
Decitabine is a DNA methyltransferase inhibitor....
|
|
KI0349 |
Danusertib(PHA-739358) |
827318-97-8 |
Danusertib is a small-molecule 3-aminopyrazole derivative with strong activity against Aurora kinases with IC50 of 13, 79, and 61 nM for Aurora A, B, and C, respectively....
|
|
KI0095 |
CYT387 |
1056634-68-4 |
CYT387 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC50 of 11 and 18 nM, respectively....
|
|
KI0518 |
CUDC-907 |
1339928-25-4 |
CUDC-907 is a potent inhibitor of both HDAC and PI3K....
|
|
KI1220 |
CUDC-101 |
1012054-59-9 |
CUDC-101 is a potent HDAC, EGFR and HER2 inhibitor with IC50 values of 4.4, 2.4, and 15.7 nM, respectively....
|
|
KI3681 |
CI994 |
112522-64-2 |
CI-994 (Tacedinaline) is an anti-cancer drug which inhibits HDAC1 with IC50 of 0.57 ?M and causes G1 cell cycle arrest, and CI-994 is in Phase III clinical trial in patients with Lung Cancer [1]....
|
|
KI0112 |
CHR-3996 |
1235859-13-8 |
CHR-3996 is a class I selective orally active histone deacetylase (HDAC) inhibitor with an IC50 of 8 nM....
|
|
KI3886 |
CEP18770 |
847499-27-8 |
....
|
