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Cat. No. Name Size Price Add Cart
KP0351 Bacterial Sortase Substrate I, FRET 1 mg $228

Product Information

Product NameBacterial Sortase Substrate I, FRET
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1015.2
Storage-20°C
Sequence
(One-Letter Code)		DABCYL-LPETG-EDANS
Sequence
(Three-Letter Code)		DABCYL - Leu - Pro - Glu - Thr - Gly - EDANS
DescriptionThis 5-amino acid peptide is a sortase substrate, C-terminal sorting signal. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Cleavage of this FRET substrate by sortase reveals the fluorescent signal, Abs/Em = 340/490 nm.
ReferencesMazmanian, S. et al. PNAS 99, 2293 (2002); Ilangovan, U. et al. PNAS 98, 6056 (2001), Ton-That, H. et al. PNAS 96, 12424 (1999); W. Navarre and O. Schneewind Microbiol. Mol. Biol. Rev. 63, 174 (1999).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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