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KP0356 BAD Peptide, biotin - labeled 1 mg $116

Product Information

Product NameBAD Peptide, biotin - labeled
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1814.1
Storage-20°C
Sequence
(One-Letter Code)
Biotin-LC-AGAGRSRHSSYPAGT
Sequence
(Three-Letter Code)
BIOTIN - LC - Ala - Gly - Ala - Gly - Arg - Ser - Arg - His - Ser - Ser - Tyr - Pro - Ala - Gly - Thr - OH
DescriptionThis BAD peptide is biotinylated at the N-terminus through 6-aminohexanoate (LC) as a spacer. Bad peptide is a pro-apoptotic member of the Bcl2 family. Dephosphorylated Bad forms heterodimers with Bcl-XL and Bcl-2, blocking their anti-apoptotic effects. Inactive Bad is phosphorylated at Ser112, Ser136, and Ser155. The phosphorylation status of Bad represents a fundamental checkpoint for apoptotic death or cell survival.
ReferencesCiornei, R. and McGillis, J. J. Immunol. 178, S117 (2007).
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