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KP0357 Bak - BH3, TAMRA - labeled 1 mg $260

Product Information

Product NameBak - BH3, TAMRA - labeled
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 2265.6
Storage-20°C
Sequence
(One-Letter Code)
GQVGRQLAIIGDDINR-K(TAMRA)-NH2
Sequence
(Three-Letter Code)
H - Gly - Gln - Val - Gly - Arg - Gln - Leu - Ala - Ile - Ile - Gly - Asp - Asp - Ile - Asn - Arg - Lys(TAMRA) - NH2
DescriptionThis peptide is derived from the BH3 domain of Bak (Flu-BakBH3). It has high-affinity binding to a surface pocket of the Bcl-XL protein that is essential for its death antagonist function. This peptide is labeled with 5-TAMRA on the side chain of lysine at the C-terminus, Abs/Em=544/572 nm..
ReferencesWang, J. et al. Canc. Res. 60, 1498 (2000); Juin, P. et al. Mol. Cell. Biol. 22, 6158 (2002).
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