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KP0358 Bak BH3 1 mg $95

Product Information

Product NameBak BH3
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1724.9
Storage-20°C
Sequence
(One-Letter Code)
GQVGRQLAIIGDDINR
Sequence
(Three-Letter Code)
H - Gly - Gln - Val - Gly - Arg - Gln - Leu - Ala - Ile - Ile - Gly - Asp - Asp - Ile - Asn - Arg - OH
DescriptionThis peptide, derived from the BH3 domain of Bak (Flu-BakBH3), has been shown to have high-affinity binding to a surface pocket of the Bcl-XL protein that is essential for its death antagonist function.
ReferencesWang, J. et al. Cancer Res.60, 1498 (2000); Juin, P. et al. Mol. Cell. Biol. 2, 6158 (2002).
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