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KP0393 BH3 BIM Peptide (52 - 71), human 1 mg $116

Product Information

Product NameBH3 BIM Peptide (52 - 71), human
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 2485.9
Storage-20°C
Sequence
(One-Letter Code)
Ac-MRPEIWIAQELRRIGDEFNA
Sequence
(Three-Letter Code)
Ac - Met - Arg - Pro - Glu - Ile - Trp - Ile - Ala - Gln - Glu - Leu - Arg - Arg - Ile - Gly - Asp - Glu - Phe - Asn - Ala - NH2
DescriptionThis amino acids 52 to 71 fragment of the BH3 domain of Bim reportedly functions as direct 'death agonist' of Bax. Bim belongs to a distinct subgroup of proapoptotic proteins that resemble other Bcl-2 family members within the BH3 domain.
ReferencesO??Reilly, L. et al. Am. J. Pathol. 157, 449 (2000), Letai A, et al. Canc. Cell 2, 183 (2002), Cartron, P. et al. Mol. Cell 16, 807 (2004), Manero, F. et al. Canc. Res. 66, 2757 (2006).
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