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Cat. No. Name Size Price Add Cart
KP0397 Bid BH3 Peptide 1 mg $116

Product Information

Product NameBid BH3 Peptide
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 2309.6
Storage-20°C
Sequence
(One-Letter Code)		EDIIRNIARHLAQVGDSMDR
Sequence
(Three-Letter Code)		H - Glu - Asp - Ile - Ile - Arg - Asn - Ile - Ala - Arg - His - Leu - Ala - Gln - Val - Gly - Asp - Ser - Met - Asp - Arg - OH
DescriptionBID is a pro-apoptotic member of the "BH3-only" (BOPS) subset of the BCL-2 family of proteins that constitute a critical control point in apoptosis. Bid is the first of the BOPs reported to bind and activate Bcl-2, Bax, and Bak. Bid serves as a death-inducing ligand that moves from the cytosol to the mitochondrial membrane to inactivate Bcl-2 or to activate Bax.
ReferencesOh, K. J. et al J. Biol. Chem. 280, 753 (2005); Oh, K. J. et al. J. Biol. Chem. 281, 36999 (2006); Manero, F. et al. Cancer Res. 66, 2757 (2006); Zhai, D. et al. J. Biol. Chem. 280, 15815 (2005); Walensky, L. et al. Mol. Cell. 24, 199 (2006); Onuki, R. et al. Proc. Natl. Acad. Sci. U S A 99, 14716 (2002); Wang, K. Gen. Develop. 10, 2859 (1996).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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