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KP0396 Bid BH3 - R9 1 mg $222

Product Information

Product NameBid BH3 - R9
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 3772.3
Storage-20°C
Sequence
(One-Letter Code)
RRRRRRRRRGEDIIRNIARHLAQVGDSMDR
Sequence
(Three-Letter Code)
H - Arg - Arg - Arg - Arg - Arg - Arg - Arg - Arg - Arg - Gly - Glu - Asp - Ile - Ile - Arg - Asn - Ile - Ala - Arg - His - Leu - Ala - Gln - Val - Gly - Asp - Ser - Met - Asp - Arg - OH
DescriptionBid BH3 is a pro-apoptotic member of the "BH3-only" subset of the BCL-2 family proteins that constitute a critical control point in apoptosis. BID BH3 interacts with Bax to induce mitochondrial outer membrane permeabilization in the apoptotic process. This peptide contains 9 Arg residues in the L-isomeric form on the N-terminus. BID Tagging with poly-arginine facilitates cell internalization.
ReferencesLetai, A. J Clin Invest 115, 2648 (2005). Mendoza, F. et al. Arch Immunol Ther Exp 53, 47 (2002).
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