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KP0462 C - Peptide - 1, rat 1 mg $251

Product Information

Product NameC - Peptide - 1, rat
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 3259.6
Storage-20°C
Sequence
(One-Letter Code)
EVEDPQVPQLELGGGPEAGDLQTLALEVARQ
Sequence
(Three-Letter Code)
H - Glu - Val - Glu - Asp - Pro - Gln - Val - Pro - Gln - Leu - Glu - Leu - Gly - Gly - Gly - Pro - Glu - Ala - Gly - Asp - Leu - Gln - Thr - Leu - Ala - Leu - Glu - Val - Ala - Arg - Gln - OH
DescriptionThis is amino acid sequence of rat C-peptide-1. C-peptide binds specifically to cell surfaces, probably to a G protein-coupled surface receptor, with subsequent activation of Ca2+-dependent intracellular signaling pathways. It also stimulates Na+-K+-ATPase and endothelial nitric oxide synthase activities. Rat C-peptide was found to diminish glucose-stimulated insulin release in rats both in vivo and in vitro.
ReferencesWahren, J. et al. Am. J. Physiol Endocrinol Metab. 278, E759 (2000).
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