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KP0488 Caloxin 2A1 1 mg $106

Product Information

Product NameCaloxin 2A1
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1479.5
Storage-20°C
Sequence
(One-Letter Code)
VSNSNWPSFPSSGGG
Sequence
(Three-Letter Code)
H-Val-Ser-Asn-Ser-Asn-Trp-Pro-Ser-Phe-Pro-Ser-Ser-Gly-Gly-Gly-OH
DescriptionCaloxins are extracellular plasma membrane (PM) Ca2+ pump inhibitors. Caloxin 2A1 is a PM Ca2+ pump inhibitor selectively binding to an extracellular domain. It inhibits Ca2+-Mg2+-ATPase in human erythrocyte leaky ghosts. Caloxin 2A1 is active at an extracellular site, the peptide can simply be added exogenously to inhibit the plasma membrane calcium ATPase (PMCA).Related peptides: Caloxin 1A1 and Caloxin 3A1.
ReferencesChaudhary, J. et al. Am. J. Physiol. Cell. Physiol. 280, C1027 (2001); Chaudhary, J. et al. Am. J. Physiol. Cell. Physiol. 290, C1341 (2006); Holmes, M. et al. Cell Calcium 33, 241 (2003); De Luisi, A. and A. Hofer J. Cell Sc. 116, 1527 (2003).
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