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KP0531 Caspase 6 (Mch2) Substrate 1r, fluorogenic(Ac - VEID)2 - Rh110 1 mg $148

Product Information

Product NameCaspase 6 (Mch2) Substrate 1r, fluorogenic(Ac - VEID)2 - Rh110
Molecular Weight 1326.4
Storage-20°C desiccated and protected from light
DescriptionRh110 (rhodamine 110)-derived caspase substrates are probably the most sensitive indicators widely used for the fluorimetric detection of various caspase activities. Cleavage of Rh110 peptides by caspases generates strongly fluorescent Rh110 that is monitored fluorimetrically at 510-530 nm with excitation of 488 nm, the most common excitation light source used in fluorescence instruments.Caspase-6 substrate
ReferencesGurtu V, et al. (1997). Fluorometric and colorimetric detection of caspase activity associated with apoptosis. Anal Biochem 251, 98-102; Martins LM, et al. (1997). Activation of multiple interleukin-1 β converting enzyme homologues in cytosol and nuclei of HL-60 cells during etoposide-induced apoptosis. J Biol Chem 272, 7421-30.
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