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Cat. No. Name Size Price Add Cart
KP0553 Cathepsin D and E FRET Substrate 1 mg $137

Product Information

Product NameCathepsin D and E FRET Substrate
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1756.1
Storage-20°C
Sequence
(One-Letter Code)		Mca-GKPILFFRLK(Dnp)-r-NH2
Sequence
(Three-Letter Code)		7 - Methoxycoumarin - 4 - Acetyl - Gly - Lys - Pro - Ile - Leu - Phe - Phe - Arg - Leu - Lys(Dnp) - D - Arg - NH2
DescriptionAn internally quenched fluorogenic substrate (Ab/Em =328/393 nm) for cathepsins D and E and not for B, H or L, obtained from the hepatopancreas (liver) of the Japanese common squid (Todarodes pacificus). The cleavage occurs at the Phe-Phe amide bond resulting in enhanced fluorescence and is used in screening cathepsin D and E inhibitors and for determining cathepsin D and E activity in tissue cell extracts.
ReferencesYasuda, Y. et al. J. Biochem. 125, 1137 (1999).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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