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KP0664 delta PKC (8 - 17); PKC d Inhibitor 1 mg $63

Product Information

Product Namedelta PKC (8 - 17); PKC d Inhibitor
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1116.2
Storage-20°C
Sequence
(One-Letter Code)
SFNSYELGSL
Sequence
(Three-Letter Code)
H - Ser - Phe - Asn - Ser - Tyr - Glu - Leu - Gly - Ser - Leu - OH
DescriptionThis peptide is derived from the V1 domain of protein kinase C (PKC)d. It inhibits phorbol 12-myristate 13-acetate (PMA)-induced PKCd translocation and activation. Inhibition of PKCd reduces ischemia damage in cardiac and cerebral cells, induces proliferation of fibroblasts, and inhibits graft coronary artery disease in mice.
ReferencesBright, R. et al. J Neurosci 24, 6880 (2004). Tanaka, M. et al. Circulation 110, 194 (2004). Braun, M and D. Mochly-Rosen. J Mol Cell Cardiol 35 895 (2003). Chen, L. et al. Proc Natl Acad Sci USA 98, 11114 (2001).
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