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Cat. No. Name Size Price Add Cart
KP0756 GALA, Pore - Forming Peptide 1 mg $228

Product Information

Product NameGALA, Pore - Forming Peptide
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 3032.4
Storage-20°C
Sequence
(One-Letter Code)		WEAALAEALAEALAEHLAEALAEALEALAA
Sequence
(Three-Letter Code)		H - Trp - Glu - Ala - Ala - Leu - Ala - Glu - Ala - Leu - Ala - Glu - Ala - Leu - Ala - Glu - His - Leu - Ala - Glu - Ala - Leu - Ala - Glu - Ala - Leu - Glu - Ala - Leu - Ala - Ala - OH
DescriptionGALA is a 30 amino acid synthetic peptide with a glutamic acid-alanine-leucine-alanine (EALA) repeat. It also contains a histidine and tryptophan residue as spectroscopic probes. This peptide was designed to explore how viral fusion protein sequences interact with membranes. It was used to study the importance of the helix length, hydrophobicity, and hydrophobic moment on the formation, structure, and function of ion channels. The membrane-interacting properties of GALA have been extensively documented. Investigations with analogs of cytotoxic peptides clarify the importance of peptide charge and the role of particular amino acids or arrays of amino acids in the conformation, membrane-binding affinity, and pore-forming abilities of these toxins.
ReferencesFrancois, N. et al. Biophys. J. 76, 2121 (1999), Li, W. et al. Adv. Drug Del. Rev.56, 967 (2004).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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