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Cat. No. Name Size Price Add Cart
KP0879 GRGDS, LC - biotin labeled 1 mg $74

Product Information

Product NameGRGDS, LC - biotin labeled
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 830
Storage-20°C
Sequence
(One-Letter Code)		Biotin-LC-GRGDS
Sequence
(Three-Letter Code)		Biotin - LC - Gly - Arg - Gly - Asp - Ser - OH
DescriptionThe GRGDS peptide contains the amino acid sequence Arg-Gly-Asp (RGD), which has been implicated as a recognition site in interactions between extracellular matrix (ECM) molecules and cell membrane receptors. RGD-containing synthetic peptides are known to inhibit attachment of endothelial cells to substrates. GRGDS peptide inhibits angiogenesis in serum-free collagen gel culture. This synthetic peptide mimics the cellular binding site of many adhesive proteins in the extracellular matrix and causes rounding and detachment of spread cells. This peptide is biotinylated through 6-aminohexanoate (LC) as a spacer.
ReferencesNicosia, R. and Bonanno, E. Am. J. Pathol. 138, 829 (1991); Kang, I-C. et al. Cancer Res. 59, 3754 (1999); S. Stickel and Y. Wang J. Cell Biol. 107, 1231 (1988).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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