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KP0930 Hirudin (54-65), sulfated 1 mg Quote

Product Information

Product NameHirudin (54-65), sulfated
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1590.6
Storage-20°C
Sequence
(One-Letter Code)
Ac-GDFEEIPEE-Y(SO3H)-LQ
Sequence
(Three-Letter Code)
Ac-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3H)-Leu-Gln-OH
DescriptionThis is amino acids 54 to 65 fragment of sulfated hirudin, a 65-residue peptide. Hirudin is found in the saliva of the leech Hirudo medicinalis. This sulfated peptide binds tightly to anion-binding exosite I of thrombin, but does not inhibit hydrolysis of synthetic peptide substrates.
ReferencesVan Deerlin, V. et al. J. Biol. Chem. 266, 20223 (1997).
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