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KP0974 Hyaluronan - Binding Peptide, biotin labeled 1 mg $132

Product Information

Product NameHyaluronan - Binding Peptide, biotin labeled
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 2012.2
Storage-20°C
Sequence
(One-Letter Code)
GAHWQFNALTVRGGGS-K(Biotin)
Sequence
(Three-Letter Code)
H - Gly - Ala - His - Trp - Gln - Phe - Asn - Ala - Leu - Thr - Val - Arg - Gly - Gly - Gly - Ser - Lys(Biotin) - OH
DescriptionThis peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.
ReferencesMahaffey, C. and ME Mummert. J Immunol 179, 8191 (2007); Mummert, M. et al. J Exp Med 192, 769 (2000).
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