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KP1015 Innate Defense Regulator - 1 (IDR - 1) 1 mg $80

Product Information

Product NameInnate Defense Regulator - 1 (IDR - 1)
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1392.8
Storage-20°C
Sequence
(One-Letter Code)
KSRIVPAIPVSLL
Sequence
(Three-Letter Code)
H - Lys - Ser - Arg - Ile - Val - Pro - Ala - Ile - Pro - Val - Ser - Leu - Leu - OH
DescriptionThis peptide is an innate defense regulator (IDR-1). IDR-1 acts through mitogen-activated protein kinase and other signaling pathways, enhances levels of monocyte chemokines while reducing pro-inflammatory cytokine responses. IDR-1 counters infection by selective modulation of innate immunity. It is protective against Gram-positive and Gram-negative pathogens in mouse models of infection.
ReferencesScott, M. et al. Nat. Biotechnol. 25, 465 (2007).
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Our products are used for research, laboratory and further evaluation purposes. They are not for human use.