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KP1016 Insulin β Chain Peptide (15 - 23) 1 mg $68

Product Information

Product NameInsulin β Chain Peptide (15 - 23)
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1009.2
Storage-20°C
Sequence
(One-Letter Code)
LYLVCGERG
Sequence
(Three-Letter Code)
H - Leu - Tyr - Leu - Val - Cys - Gly - Glu - Arg - Gly - OH
DescriptionThis is amino acids 15 to 23 fragment of the insulin β chain recognized by islet-associated T cells. This peptide is also known as INS. It was used in diabetes studies to assay the IFN-β and IL-17 production by diabetogenic CD4 or CD8 T cells. This peptide stains the INS-reactive CTL clone, but doesn′t stain the splenic CD8+ T cells from NOD or 8.3-TCR-transgenic NOD mice.
ReferencesHu, C. et al. J. Clin. Invest. 117, 3857 (2007); Amrani, A. et al. Nature 406, 739 (2000).
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