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Cat. No. Name Size Price Add Cart
KP1029 IRBP (1-20), human 1 mg $116

Product Information

Product NameIRBP (1-20), human
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 2194.6
Storage-20°C
Sequence
(One-Letter Code)		GPTHLFQPSLVLDMAKVLLD
Sequence
(Three-Letter Code)		H-Gly-Pro-Thr-His-Leu-Phe-Gln-Pro-Ser-Leu-Val-Leu-Asp-Met-Ala-Lys-Val-Leu-Leu-Asp-OH
DescriptionThis peptide is a 1 to 20 amino acid fragment of the interphotoreceptor retinoid binding protein (IRBP). IRBP is a 140-kDa glycolipoprotein residing in the interphotoreceptor matrix between the neural retina and the retinal pigment epithelium. Human IRBP peptide 1-20 contains a major epitope for the H-2b haplotype. Immunization with IRBP (1-20) induces T-cell-mediated experimental autoimmune uveoretinitis (EAU) disease. The pathology of disease induced by the peptide, or by adoptive transfer of cells specific to the peptide, is similar to that induced by the whole IRBP protein.
ReferencesAvichezer, D. et al. Invest. Ophthalmol. Visual Sci. 41, 127 (2000).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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