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KP1031 IRBP, Interphotoreceptor Retinoid Binding Protein Fragment 1 mg $116

Product Information

Product NameIRBP, Interphotoreceptor Retinoid Binding Protein Fragment
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 2209.5
Storage-20°C
Sequence
(One-Letter Code)
SGIPYIISYLHPGNTILHVD
Sequence
(Three-Letter Code)
H-Ser-Gly-Ile-Pro-Tyr-Ile-Ile-Ser-Tyr-Leu-His-Pro-Gly-Asn-Thr-Ile-Leu-His-Val-Asp-OH
DescriptionThis 20-residue peptide, a major pathogenic T-cell epitope (161-180), is present in the first homologous repeat of the interphotoreceptor retinoid binding protein peptide (IRBP). It has been shown to induce posterior uveitis (EAU).
ReferencesRef: Sonoda, K. et al. J. Immunol. 171, 2652 (2003); Read, RW. and SR. Barnum, ARVO Meeting Abstracts 43, 2281 (2002); Silver, P. et al. Invest. Ophthal. Vis. Sci. 36, 946 (1995); Karabekian, Z. et al. Invest. Ophthalmol. Vis. Sci. 46, 3769 (2005).
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