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KP1086 Linear C5a Receptor Antagonist, mouse, human 1 mg $95

Product Information

Product NameLinear C5a Receptor Antagonist, mouse, human
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 886.1
Storage-20°C
Sequence
(One-Letter Code)
FKP-(D-Cha)-Wr
Sequence
(Three-Letter Code)
H - Phe - Lys - Pro - D - Cha - Trp - D - Arg - OH
DescriptionThis linear peptide is derived from the C-terminus of the chemokine, complement fragment 5 anaphylatoxin (C5a). This peptide functions to inhibit C5a binding and function at human and rat C5a receptors. C5a is crucial to triggering cellular immune responses and its overexpression is involved in arthritis, Alzheimer's disease, cystic fibrosis, systemic lupus erythematosus, and other immunoinflammatory diseases
ReferencesHigginbottom, A. J Biol Chem 280, 17831 (2005); Buck, E. et al. PNAS 102, 2719 (2005).
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Our products are used for research, laboratory and further evaluation purposes. They are not for human use.