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Cat. No. Name Size Price Add Cart
KP1101 LyP - 1, Peptide 1 1 mg $116

Product Information

Product NameLyP - 1, Peptide 1
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 992.2
Storage-20°C
Sequence
(One-Letter Code)		CGNKRTRGC (S-S Bonded)
Sequence
(Three-Letter Code)		H - Cys - Gly - Asn - Lys - Arg - Thr - Arg - Gly - Cys - OH (S - S Bonded)
DescriptionLyP-1 recognizes lymphatics and tumor cells in certain tumors, but not lymphatics in normal tissues. Screening on breast carcinoma xenografts shows positive to cyclic 9-amino-acid peptide, LyP-1. The LyP-1 also recognizes an osteosarcoma xenograft, and spontaneous prostate and breast cancers in transgenic mice. LyP-1 peptide is detected in tumor structures that are positive for several lymphatic endothelial markers and negative for blood vessel markers. LyP-1 accumulates in the nuclei of the putative lymphatic cells, and in the nuclei of tumor cells.
ReferencesZhang, L. et al. Canc. Res. 66, 5696 (2006); Akerman, M. et al. PNAS 99, 12617 (2002); Laakkonen, P.et al. Nat. Med. 8, 751 (2002).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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