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Cat. No. Name Size Price Add Cart
KP0049 [Lys(Ac)373] - p53 (368 - 393), p53 K373(Ac), biotin - labeled, human 1 mg $355

Product Information

Product Name[Lys(Ac)373] - p53 (368 - 393), p53 K373(Ac), biotin - labeled, human
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 3481
Storage-20°C
Sequence
(One-Letter Code)		Biotin-KGGHLKSK-K(Ac)-GQSTSRHKKLMFKTEGPDSD-NH2
Sequence
(Three-Letter Code)		Biotin - Lys - Gly - Gly - His - Leu - Lys - Ser - Lys - Lys(Ac) - Gly - Gln - Ser - Thr - Ser - Arg - His - Lys - Lys - Leu - Met - Phe - Lys - Thr - Glu - Gly - Pro - Asp - Ser - Asp - NH2
DescriptionThis peptide is tumor suppressor protein, p53 (368-393). There is a biotinylated lyine followed by a GG linker at the N-terminal and an acetylated lysine at lysine 373. Activation of the p53 protein results in the transcription of antiproliferative proteins and induction of apoptosis. The p53 tumor suppressor is a principal mediator of growth arrest, senescence, and apoptosis in response to a broad array of cellular damage.
ReferencesKanovsky, M. et al. Proc Natl Acad Sci 98, 12438 (2001).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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