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KP0053 [Lys(Ac)382] - p53 (368 - 393), p53 K382(Ac), biotin - labeled, human 1 mg $355

Product Information

Product Name[Lys(Ac)382] - p53 (368 - 393), p53 K382(Ac), biotin - labeled, human
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 3481
Storage-20°C
Sequence
(One-Letter Code)
Biotin-KGGHLKSKKGQSTSRHK-K(Ac)-LMFKTEGPDSD-NH2
Sequence
(Three-Letter Code)
Biotin - Lys - Gly - Gly - His - Leu - Lys - Ser - Lys - Lys - Gly - Gln - Ser - Thr - Ser - Arg - His - Lys - Lys(Ac) - Leu - Met - Phe - Lys - Thr - Glu - Gly - Pro - Asp - Ser - Asp - NH2
DescriptionThis peptide is tumor suppressor protein p53 (368-393). There is a biotinylated lysine follwed by a GG linker at the N-terminal and is acetylated at lysine 382. p53 is an ideal tumor suppressor gene because of its ability to control cell proliferation, and senescence. In response to cell stress, cell damage, or ectopic oncogene, p53 also mediates apoptosis.
ReferencesGhosh, A. et al. Mol. Cell Biol. 24, 7987 (2004).
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