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KP0069 [Lys(Me2)382] - p53 (377 - 387); p53K382Me2 1 mg $342

Product Information

Product Name[Lys(Me2)382] - p53 (377 - 387); p53K382Me2
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1404.7
Storage-20°C
Sequence
(One-Letter Code)
TSRHK-K(Me2)-LMFKT
Sequence
(Three-Letter Code)
H - Thr - Ser - Arg - His - Lys - Lys(Me2) - Leu - Met - Phe - Lys - Thr - OH
Descriptionp53K382Me2 is derived from amino acid residues 377-387 of human p53 tumor suppressor protein, with dimethylation at Lys382. DNA damage induces increased levels of this peptide, which is recognized by p53-binding protein 1 (53BP1). 53BP1 interacts with p53 and modulates its transactivation.
ReferencesKachirskaia, I. et al. J Biol Chem 283, 34660 (2008).
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