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KP0075 [Lys0] - Bradykinin (Kallidin) 5 mg $53

Product Information

Product Name[Lys0] - Bradykinin (Kallidin)
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1188.4
Storage-20°C
Sequence
(One-Letter Code)
KRPPGFSPFR
Sequence
(Three-Letter Code)
H - Lys - Arg - Pro - Pro - Gly - Phe - Ser - Pro - Phe - Arg - OH
DescriptionBradykinins (BK) and related kinins are potent inflammatory mediators produced during acute and chronic inflammation. The two main 'kinins' in mammals are the nonapeptide bradykinin, BK (1-9) and the decapeptide kallidin (KD), [Lys0]-BK(1-10). Their biological actions are mediated by two distinct receptors, termed B1 and B2. BK and [Lys0]-BK are peptides which are released at high nanomolar concentrations into the tear-film of ocular allergic patients.
ReferencesRef: Altamura, M. et al Regul. Pept. 80, 13 (1999); Siebeck, M. et al. Immunopharmacol. 40, 49 (1998); Wiernas, T. et al. Br. J. Pharmacol. 121, 649 (1997).
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