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Cat. No. Name Size Price Add Cart
KP1125 Magainin 1 1 mg $137

Product Information

Product NameMagainin 1
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 2409.9
Storage-20°C
Sequence
(One-Letter Code)		GIGKFLHSAGKFGKAFVGEIMKS
Sequence
(Three-Letter Code)		H - Gly - Ile - Gly - Lys - Phe - Leu - His - Ser - Ala - Gly - Lys - Phe - Gly - Lys - Ala - Phe - Val - Gly - Glu - Ile - Met - Lys - Ser - OH
DescriptionMagainins are peptide antibiotics with antibacterial and antiparasitic activities, originally extracted from the skin of Xenopus laevis. Magainin 1 and 2 are closely related peptides of 23 amino acids each and differ by two substitutions. These antimicrobial peptides have broad-spectrum, non-specific activity against a wide range of micro-organisms, including viruses, gram-positive and gram-negative bacteria, protozoa, yeasts and fungi, and may also be hemolytic and cytotoxic to cancer cells. Magainin 1 is a bactericide. Both Magainin 1 and 2 exhibit inhibitory action toward Herpes simplex virus type 1(HSV-1) and HSV-2.
ReferencesWilliams, RW. et al. Biophysical J. 53, 631A (1988); Morvan, A. et al. Mol. Mar. Biol. Biotechnol. 3, 327 (1994); Matanic, A. et al. Int. J. Antimicrob. Agents 23, 382 (2004); Zasloff, M. Proc. Natl. Acad. Sci. 84, 5449 (1987).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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