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KP1139 Mastoparan 7 1 mg $89

Product Information

Product NameMastoparan 7
Molecular Weight 1421.8
Storage-20°C
Sequence
(One-Letter Code)
INLKALAALAKALL-NH2
Sequence
(Three-Letter Code)
H - Ile - Asn - Leu - Lys - Ala - Leu - Ala - Ala - Leu - Ala - Lys - Ala - Leu - Leu - NH2
DescriptionThis mastoparan modification, referred as mastoparan 7 (MP7), has Lys12 replaced by Ala12, and Ile13 replaced by Leu13. Mastoparan is an amphiphilic tetradecapeptide isolated from wasp venom. It is known to possess a variety of biological activities including mast cell degranulation, mobilization of Ca2+ from cerebellar microsomes and sarcoplasmic reticulum, and modulation of various enzymes. MP7 retains the ability to form α-helices in lipids and have similar hydrophobic moments to mastoparan. Mastoparan also inhibits the ATPase.
ReferencesLongland, C. et al. J. Biol. Chem. 274, 14799 (1999).
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