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KP1211 MOG (8 - 21) 1 mg $89

Product Information

Product NameMOG (8 - 21)
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1486.7
Storage-20°C
Sequence
(One-Letter Code)
PGYPIRALVGDEAE
Sequence
(Three-Letter Code)
H - Pro - Gly - Tyr - Pro - Ile - Arg - Ala - Leu - Val - Gly - Asp - Glu - Ala - Glu - OH
DescriptionThis peptide is amino acids 8 to 21 fragment of the myelin oligodendrocyte glycoprotein (MOG). It induces relapsing experimental autoimmune encephalomyelitis (EAE) in mice associated with broadening of the autoimmune repertoire. Subtle changes in MOG (8-21) dramatically influences disease susceptibility and T-cell responses in vitro.
ReferencesHeijmans, N. et al. J. Neuroimmunol. 167, 23 (2005), Smith, P. et al. J. Neuroimmunol. 164, 76 (2005).
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