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KP1215 MOG (92-106) 1 mg $89

Product Information

Product NameMOG (92-106)
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1824.9
Storage-20°C
Sequence
(One-Letter Code)
DEGGYTCFFRDHSYQ
Sequence
(Three-Letter Code)
H - Asp - Glu - Gly - Gly - Tyr - Thr - Cys - Phe - Phe - Arg - Asp - His - Ser - Tyr - Gln - OH
DescriptionThis is amino acids 92 to 106 fragment of the myelin oligodendrocyte glycoprotein (MOG). Mice with MOG (92-106)-induced experimental autoimmune encephalomyelitis develop extensive B cell reactivity against secondary myelin antigens. Despite the fact that this MOG peptide induces only weak T cell responses, MOG-induced autoimmunity is very severe. This peptide is encephalitogenic in SJL mice, DA rats, and rhesus monkeys.
ReferencesBischof, F. et al. J. Immunol. 173, 600 (2004).
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