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Cat. No. Name Size Price Add Cart
KP1219 MUC1 TR 1 mg $116

Product Information

Product NameMUC1 TR
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1887
Storage-20°C
Sequence
(One-Letter Code)		PAPGSTAPPAHGVTSAPDTR
Sequence
(Three-Letter Code)		H - Pro - Ala - Pro - Gly - Ser - Thr - Ala - Pro - Pro - Ala - His - Gly - Val - Thr - Ser - Ala - Pro - Asp - Thr - Arg - OH
DescriptionThis 20-amino-acid tandem repeat (TR) sequence belongs to the extracellular domain of mucin. It contains five possible O-glycan attachment sites and this sequence is repeated 20-120 times. The action of several GalNAc-Ts are needed to glycosylate all five acceptor sites. MUC1 is a transmembrane mucin expressed on the apical surface of most epithelial cells, including the mammary glands, and also on hematopoietic cells and in bone marrow. MUC1 is highly overexpressed in many forms of cancer, in particular breast carcinomas.
ReferencesOlson, F. et al. Glycobiol.15, 177 (2005).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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