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KP1224 MUC5AC - 13 1 mg $237

Product Information

Product NameMUC5AC - 13
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1704.6
Storage-20°C
Sequence
(One-Letter Code)
GTTPSPVPTTST-T*-SAP
Sequence
(Three-Letter Code)
H - Gly - Thr - Thr - Pro - Ser - Pro - Val - Pro - Thr - Thr - Ser - Thr - Thr* - Ser - Ala - Pro - OH (Thr* = GalNac labeled Thr)
DescriptionThis glycopeptide is an N-acetyl galactosamine (GalNAc)-modified MUC5AC mucin peptide containing the single site of threonine 13 labeled with GalNAc (T∗). Polypeptide N-acetylgalactosaminyltransferase (ppGaNTase) catalyzes the transfer of GalNAc from the nucleotide sugar UDP-GalNAc to threonine. The MUC5AC gene is mainly expressed in gastric and tracheo-bronchial mucosae, and some tumors.
ReferencesTen Hagen, K. et al. J. Biol. Chem. 277, 22616 (2002).
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